Formulated specifically to be used with tretinoin. Contains 2% hydroquinone, which is used for the treatment of pigmentation.
DESCRIPTION
Achieve a brighter, more even skin tone with ZO Pigment Control + Blending Crème 2% HQ, a medical-grade skin brightener formulated to reduce hyperpigmentation, melasma, and discoloration. Designed to be used in combination with tretinoin, this potent treatment helps to correct uneven skin tone, suppress future pigment formation, and enhance the penetration of active ingredients for maximum results.
✔ Clinically proven to lighten melasma, freckles, and sun damage
✔ Improves skin hydration while reducing irritation from hydroquinone
✔ Supports long-term pigment suppression and overall skin health
BENEFITS
Gradually lightens melasma, sunspots, and post-inflammatory hyperpigmentation
Enhances absorption of active ingredients for deeper skin penetration
Hydrates and strengthens newly exposed skin
Suppresses future pigmentation and corrects existing discoloration
Optimized for use with tretinoin to accelerate results
HOW TO USE
Directions AM & PM Routine
- Cleanse skin thoroughly before applying
- Apply a thin, even layer to affected areas twice daily or as directed by a healthcare practitioner
- Test skin sensitivity by applying to a small area first
- Follow with sunscreen during the day to protect treated skin from sun exposure. See enclosed package insert for full prescribing information.
⚠ Hydroquinone should not be used for more than 3 months consecutively. Consult a healthcare professional for a weaning-off protocol to prevent rebound pigmentation.
GUIDELINES
Important Warnings & Precautions
- Important: This product requires a skincare consultation before purchase. Check first if you are a good candidate for this product. Call the clinic at 647-615-0223 for guidance.
- Not recommended for pregnant or breastfeeding individuals
- Avoid applying to irritated, sunburned, or broken skin
- Possible skin reactions include mild redness, peeling, and dryness – this indicates skin renewal
- Discontinue use if irritation persists and consult a healthcare provider
Precautionary Measures
✔ Patch Test First – Apply a small amount on an unbroken area of skin and wait 24 hours to check for any reaction.
✔ Avoid If You Have a Sulfite Allergy – Consult a doctor before use.
✔ Use Sunscreen – Hydroquinone increases sun sensitivity, so daily SPF is essential.
✔ Consult a Healthcare Practitioner – Especially if you have a history of allergies, asthma, or sensitive skin.
If irritation, excessive redness, or allergic symptoms occur, discontinue use and consult a medical professional.
ADVANCED INFORMATION
Powerful Active Ingredients:
2% Hydroquinone – A gold-standard ingredient that suppresses melanin production to lighten dark spots and even skin tone
Glycolic Acid & Ascorbic Acid – Gently exfoliates and boosts skin clarity
Glycerin – Hydrates newly revealed skin, preventing dryness and irritation
Saponin – Helps reduce inflammation and enhances skin tolerance to hydroquinone
Vitamin E and Butylated Hydroxytoluene – Provides antioxidant properties
Ethylhexyl Palmitate & Phenyl Trimethicone – Restores skin barrier and optimizes absorption of active ingredients
Other Ingredients:
- Sodium Metabisulfite – A sulfite that may cause allergic reactions, including hives, itching, and asthma-like symptoms, especially in sulfite-sensitive individuals.
- Glycolic Acid & Ascorbic Acid – May cause irritation, redness, or sensitivity, particularly in those with sensitive skin or allergies to AHAs (alpha hydroxy acids).
- Saponins – While generally well-tolerated, some individuals may experience skin irritation or sensitivity.
- Sodium Lauryl Sulfate (SLS) – Can be drying or irritating for individuals with sensitive skin.
- Fragrances or Preservatives – Some individuals may have contact dermatitis from certain preservatives or inactive ingredients in the formulation.
📞 Call us at 647-615-0223 to book a skincare consultation and create a personalized hyperpigmentation treatment plan!
ZO Pigment Control + Blending Cream 2% HQ
Save 15% on first order
80 mL / 2.7 Fl. Oz.




